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IL15RA 抗体 (Biotin)

IL15RA 适用: 人 WB, IHC, FACS, CMCD, Dep, IP 宿主: 小鼠 Monoclonal JM7A4 Biotin
产品编号 ABIN2660994
发货至: 中国
  • 抗原 See all IL15RA 抗体
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This IL15RA antibody is conjugated to Biotin
    应用范围
    • 44
    • 22
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    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Complement Mediated Cell Depletion (CMCD), Depletion (Dep), Immunoprecipitation (IP)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    克隆位点
    JM7A4
    亚型
    IgG2b kappa
    Top Product
    Discover our top product IL15RA Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    别名
    CD215 (IL15RA 产品)
    别名
    IL15RA antibody, CD215 antibody, AA690181 antibody, IL-15RA antibody, interleukin 15 receptor subunit alpha antibody, interleukin 15 receptor, alpha chain antibody, IL15RA antibody, Il15ra antibody
    背景
    IL-15 receptor α (IL-15Rα) is a cytokine receptor with the structural homology to IL-2Rα (CD25). Both α receptors contain a group of β sandwich protein called sushi domains. Similar to IL-2Rα, IL-15Rα is able to form a heterotrimer with their β chain (CD122) and common γ chain (γc, CD132). But unlike IL-2Rα subunit, IL-15Rα itself binds to IL-15 with equivalent high affinity compared with the heterotrimeric complex. IL-15Rα is expressed as soluble or transmembrane forms by variety cells, such as activated monocytes, dendritic cells, CD8+ memory T cells, NK or NKT cells. IL-15Rα by itself forms stable complexes with IL-15 on cell surface and presents IL-15 in trans to neighboring cells. IL-15, like IL-2, is a pleiotropic four-helix bundle cytokine and plays a key role in promoting T and B cell survival and proliferation, preferentially in memory CD8+ T cell proliferation, and NK/NKT cell development.
    途径
    JAK/STAT Signaling
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