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2B4 抗体 (Biotin)

CD244 适用: 小鼠 FACS 宿主: 小鼠 Monoclonal m2B4 (B6)458-1 Biotin
产品编号 ABIN2660830
发货至: 中国
  • 抗原 See all 2B4 (CD244) 抗体
    2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
    适用
    • 61
    • 25
    • 12
    小鼠
    宿主
    • 53
    • 8
    • 4
    小鼠
    克隆类型
    • 55
    • 10
    单克隆
    标记
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    • 2
    • 2
    • 2
    • 2
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    • 2
    • 1
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    This 2B4 antibody is conjugated to Biotin
    应用范围
    • 56
    • 26
    • 26
    • 25
    • 20
    • 9
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    • 1
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    克隆位点
    M2B4 (B6)458-1
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD244 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
    别名
    CD244.2 (CD244 产品)
    别名
    CD244 antibody, 2B4 antibody, NAIL antibody, NKR2B4 antibody, Nmrk antibody, SLAMF4 antibody, C9.1 antibody, F730046O15Rik antibody, Ly90 antibody, CD244 molecule antibody, CD244 natural killer cell receptor 2B4 antibody, CD244 antibody, Cd244 antibody
    背景
    Mouse CD244, also known as 2B4, is a receptor belonging to the CD2 family of proteins involved in non- MHC-restricted cytotoxicity. It is expressed on all natural killer (NK) cells, IL-2 activated NK (LAK) cells, NKT cells, and a subset of T lymphocytes, including dendritic epidermal T cells. There are at least two isoforms of CD244.2 proteins that differ in the length of the cytoplasmic domain. The long form functions in an inhibitory manner, while the short form functions in an activating manner. The ligand of CD244 is CD48, which is expressed on all hematopoietic cells. It was reported that CD244 interaction with CD48 is essential for IL-2-driven expansion and activation of murine NK cells.
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