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Thrombomodulin 抗体 (Biotin)

This anti-Thrombomodulin antibody is a 小鼠 单克隆 antibody detecting Thrombomodulin in ICFC. Suitable for 人.
产品编号 ABIN2660817
发货至: 中国

Quick Overview for Thrombomodulin 抗体 (Biotin) (ABIN2660817)

抗原

See all Thrombomodulin (THBD) 抗体
Thrombomodulin (THBD)

适用

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  • 39
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  • 2
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宿主

  • 77
  • 74
  • 6
  • 2
  • 2
小鼠

克隆类型

  • 93
  • 67
  • 1
单克隆

标记

  • 80
  • 21
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This Thrombomodulin antibody is conjugated to Biotin

应用范围

  • 102
  • 77
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Intracellular Flow Cytometry (ICFC)

克隆位点

M80
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    Thrombomodulin (THBD)

    别名

    CD141

    背景

    CD141 is a 75 kD, single chain, type I membrane glycoprotein also known as thrombomodulin, TM, THRM, THBD, and fetomodulin. CD141 is an important cofactor in the protein C anticoagulant system. After binding to its ligand thrombin, CD141 activates protein C, which degrades clotting factors Va and VIIIa, and as a consequence the amount of thrombin is reduced. CD141 is expressed on macrophages, monocytes, a subpopulation of myeloid dendritic cells, vascular endothelial cells, and keratinocytes. Besides anti-coagulation function, CD141 is also involved in embryonic and atherosclerotic plaque development.
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