Thrombomodulin 抗体 (Biotin)
Quick Overview for Thrombomodulin 抗体 (Biotin) (ABIN2660817)
抗原
See all Thrombomodulin (THBD) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
 - The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
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亚型
 - IgG1 kappa
 
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应用备注
 - Optimal working dilution should be determined by the investigator.
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限制
 - 仅限研究用
 
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浓度
 - 0.5 mg/mL
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缓冲液
 - Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Protect from prolonged exposure to light. Do not freeze.
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储存条件
 - 4 °C
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储存方法
 - The antibody solution should be stored undiluted between 2°C and 8°C.
 
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- Thrombomodulin (THBD)
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别名
 - CD141
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背景
 - CD141 is a 75 kD, single chain, type I membrane glycoprotein also known as thrombomodulin, TM, THRM, THBD, and fetomodulin. CD141 is an important cofactor in the protein C anticoagulant system. After binding to its ligand thrombin, CD141 activates protein C, which degrades clotting factors Va and VIIIa, and as a consequence the amount of thrombin is reduced. CD141 is expressed on macrophages, monocytes, a subpopulation of myeloid dendritic cells, vascular endothelial cells, and keratinocytes. Besides anti-coagulation function, CD141 is also involved in embryonic and atherosclerotic plaque development.
 
抗原
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