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IL-22 抗体 (AA 34-179) (Biotin)

This anti-IL-22 antibody is a 山羊 多克隆 antibody detecting IL-22 in IHC, FACS, IP 和 IF. Suitable for 小鼠.
产品编号 ABIN2660790
发货至: 中国

Quick Overview for IL-22 抗体 (AA 34-179) (Biotin) (ABIN2660790)

抗原

See all IL-22 (IL22) 抗体
IL-22 (IL22) (Interleukin 22 (IL22))

适用

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小鼠

宿主

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  • 10
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  • 1
山羊

克隆类型

  • 78
  • 33
  • 2
多克隆

标记

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This IL-22 antibody is conjugated to Biotin

应用范围

  • 82
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Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)

克隆位点

Poly5164
  • 抗原表位

    • 23
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    AA 34-179

    纯化方法

    The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

    免疫原

    AA 34-179 (Accession# NM_016971), was expressed in E. coli.

    亚型

    Ig Fraction, IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 1 % BSA and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    IL-22 (IL22) (Interleukin 22 (IL22))

    别名

    IL-22

    背景

    IL-22 is a cytokine structurally related to IL-10. Mouse IL-22 consists of 179 amino acids and has a predicted molecular weight of 20 kD. It is secreted primarily by Th17, Th1, Th2, lymphoid tissue inducer cells (LTi), and subsets of natural killer cells. It has been reported that aryl hydrocarbon receptor (AhR) expression is essential for the production of IL-22 by TCRγδ T cells. AhR activation increases Th17 polarization and induces IL-22 production. IL-22 functions by engaging the heterodimeric IL-22 receptor (IL-22R) complex, consisting of two receptor subunits, IL-22R1 and IL-10Rβ. IL-22 acts on nonhematopoietic tissue cells, such as epithelial cells of the digestive and respiratory systems and keratinocytes of the skin. IL-22 is involved in inflammatory processes such as dermal inflammation, psoriasis, inflammatory bowel disease, hepatitis, and Crohn's disease. Moreover, it plays a critical role in mucosal immunity and the wound healing process.
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