GNLY 抗体 (Biotin)
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北京 101111
Quick Overview for GNLY 抗体 (Biotin) (ABIN2660772)
抗原
See all GNLY 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
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亚型
- IgG1 kappa
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anti-Granulysin (GNLY) (AA 23-120) antibody
GNLY 适用: 人 ELISA, WB, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Granulysin (GNLY) (AA 46-145) antibodyGNLY 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2A6 unconjugated
anti-Granulysin (GNLY) (AA 23-145) antibodyGNLY 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Granulysin (GNLY) antibodyGNLY 适用: 人 FACS 宿主: 小鼠 Monoclonal B-L38 unconjugated
anti-Granulysin (GNLY) (AA 1-145) antibodyGNLY 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Granulysin (GNLY) (C-Term) antibodyGNLY 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from prolonged exposure to light. Do not freeze.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- GNLY (Granulysin (GNLY))
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别名
- Granulysin
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背景
- Granulysin is a cytolytic protein present in granules of human natural killer (NK) cells and activated cytotoxic T lymphocytes (CTLs). Granulysin is synthesized as a 15 kD precursor, which is then cleaved at both the amino- and carboxy-termini into a 9 kD activated form. The 9 kD granulysin is released into the intercellular space between target and effector cells via a granule exocytosis pathway. The 9 kD granulysin is a chemoattractant for T lymphocytes, monocytes, and other inflammatory cells and activates the expression of a number of cytokines, including RANTES, MCP-1, MCP-3, MIP-1α, IL-1, IL-6, IL-10 and IFN-α. High serum levels of granulysin are associated with cytotoxic T cell and NK cell activity, and may thus represent a soluble biomarker for host-cellular immune responses. Serum granulysin has also been proposed as a biomarker for the Th1/Th2 balance. At the cellular level, granulysin may serve as a favorable prognostic marker for certain types of cancer.
抗原
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