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Cutaneous Lymphocyte Antigen 抗体

This anti-Cutaneous Lymphocyte Antigen antibody is a 大鼠 单克隆 antibody detecting Cutaneous Lymphocyte Antigen in FACS. Suitable for 人 和 小鼠.
产品编号 ABIN2660530
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Cutaneous Lymphocyte Antigen 抗体 (ABIN2660530)

抗原

Cutaneous Lymphocyte Antigen

适用

人, 小鼠

宿主

大鼠

克隆类型

单克隆

应用范围

Flow Cytometry (FACS)

克隆位点

HECA-452
  • 纯度

    This antibody is at > 85 % purity.

    亚型

    IgM kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    Cutaneous Lymphocyte Antigen

    背景

    Cutaneous lymphocyte antigen (CLA) is a 140 kD homodimer protein recognized by a unique mAb, HECA-452. It is expressed on T cells in skin, subsets of peripheral blood memory T cells, NK cells, memory B cells and dendritic cells as well as on monocytes, granulocytes, and activated endothelial cells. CLA is a carbohydrate epitope of sialic acid and fucose-modified P-selectin glycoprotein ligand-1 (PSGL-1), a surface glycoprotein expressed on the majority of peripheral blood leukocytes. CLA is a ligand for E-selectin, P-selectin, and L-selectin. It plays a role in memory lymphocyte homing, tethering, and rolling.
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