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CD93 抗体 (PerCP-Cy5.5)

CD93 适用: 小鼠 WB, IHC, CyTOF, ELISA (Capture), Neut, ELISPOT (Capture), ICFC 宿主: 大鼠 Monoclonal AA4-1 PerCP-Cy5.5
产品编号 ABIN2660251
发货至: 中国
  • 抗原 See all CD93 抗体
    CD93
    适用
    • 63
    • 30
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    小鼠
    宿主
    • 50
    • 19
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    大鼠
    克隆类型
    • 51
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    单克隆
    标记
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    This CD93 antibody is conjugated to PerCP-Cy5.5
    应用范围
    • 34
    • 24
    • 19
    • 15
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    • 13
    • 8
    • 6
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    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), Cytometry by Time of Flight (CyTOF), ELISA (Capture), Neutralization (Neut), ELISpot (Capture) (ELISPOT (Capture)), Intracellular Flow Cytometry (ICFC)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
    克隆位点
    AA4-1
    亚型
    IgG2b kappa
    Top Product
    Discover our top product CD93 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD93
    别名
    CD93 (CD93 产品)
    物质类
    Chemical
    背景
    CD93 is a 130-140 kD C-type lectin-like type I transmembrane protein, also known as complement component 1, q subcomponent (C1qR1), C1qRp collectin receptor (C1qRp), or AA4 antigen. It is a receptor expressed on immature B lymphocytes, hematopoietic progenitors and stem cells in adult bone marrow, fetal liver, and the embryonic yolk sac. CD93 expression levels on splenic immature/transitional B cells is much lower than in bone marrow. It is reinduced during plasma cell differentiation and plays an important role in maintaining plasma cells in bone marrow niches. Immature dendritic cells express CD93 and down-regulate this molecule upon maturation, suggesting they play a role in uptake of particles. CD93 is also expressed on monocytes, macrophages, and endothelial cells. Macrophages from CD93 (-/-) mice had a significant phagocytic defect in the clearance of apoptotic cells in vivo, indicating CD93 may contribute to the in vivo clearance of dying cells. The idea that CD93 binds to C1q remains controversial.
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