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Leucine Peptidase 抗体 (PerCP-Cy5.5)

适用: 小鼠 FACS, IP, CyTOF, IHC, WB 宿主: 小鼠 Monoclonal TW7-16B4 PerCP-Cy5.5
产品编号 ABIN2660221
发货至: 中国
  • 抗原
    Leucine Peptidase
    适用
    小鼠
    宿主
    小鼠
    克隆类型
    单克隆
    标记
    PerCP-Cy5.5
    应用范围
    Flow Cytometry (FACS), Immunoprecipitation (IP), Cytometry by Time of Flight (CyTOF), Immunohistochemistry (IHC), Western Blotting (WB)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
    克隆位点
    TW7-16B4
    亚型
    IgG1 kappa
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    Leucine Peptidase
    别名
    LAP
    背景
    Transforming growth factor beta (TGF-β) is a cytokine that has critical functions in the immune response by regulating Treg and Th17 cells. TGF-β is first synthesized as pro-TGF-β and then it is cleaved by furin proprotein convertase in the Golgi apparatus to produce the dimeric propeptides called latency-associate peptide (LAP) that non-covalently associates with the dimeric mature TGF-β to prevent its activity. This complex can further associate with latent-TGF-β-binding protein (LTBP) to produce a large latent form for deposition onto the extracellular matrix. The latent-TGF-β can be expressed on the membrane of activated Treg cells, immature dendritic cells, megakaryocytes, and platelets.
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