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CCR7 抗体 (PerCP)

This anti-CCR7 antibody is a 小鼠 单克隆 antibody detecting CCR7 in FACS. Suitable for 人.
产品编号 ABIN2659802
发货至: 中国

Quick Overview for CCR7 抗体 (PerCP) (ABIN2659802)

抗原

See all CCR7 抗体
CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CCR7 antibody is conjugated to PerCP

应用范围

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Flow Cytometry (FACS)

克隆位点

G043H7
  • 交叉反应

    Cynomolgus, 猕猴, Baboon

    纯化方法

    The antibody was purified by affinity chromatography and conjugated with PerCP under optimal conditions. The solution is free of unconjugated PerCP and unconjugated antibody.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

    别名

    CD197

    背景

    CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Naive T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T-helper cells, this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis.

    途径

    Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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