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ITGA2 抗体 (PE-Dazzle™ 594)

This PE-Dazzle™ 594-conjugated 大鼠 单克隆 anti-ITGA2 antibody (Clone DX5) specifically detects ITGA2 in FACS 和 IF. The antibody is reactive with 小鼠 samples.
产品编号 ABIN2659735
发货至: 中国
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Quick Overview for ITGA2 抗体 (PE-Dazzle™ 594) (ABIN2659735)

抗原

See all ITGA2 抗体
ITGA2 (Integrin alpha 2 (ITGA2))

适用

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小鼠

宿主

  • 82
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  • 5
  • 5
大鼠

克隆类型

  • 109
  • 65
单克隆

标记

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This ITGA2 antibody is conjugated to PE-Dazzle™ 594

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

DX5
  • 纯化方法

    The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions. The solution is free of unconjugated PE/Dazzle™ 594 and unconjugated antibody.

    亚型

    IgM kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    ITGA2 (Integrin alpha 2 (ITGA2))

    别名

    CD49b

    背景

    DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

    途径

    CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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