CXCR4 抗体 (PE/Dazzle™ 594)
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- 抗原 See all CXCR4 抗体
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CXCR4 antibody is conjugated to PE/Dazzle™ 594
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应用范围
- Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR), Cytometry by Time of Flight (CyTOF), Stimulation (St)
- 交叉反应
- Chimpanzee, Baboon, Cynomolgus, 猕猴, Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops), Sooty mangabey (Cercocebus atys), Green Monkey (Chlorocebus sabaeus)
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions. The solution is free of unconjugated PE/Dazzle™ 594 and unconjugated antibody.
- 克隆位点
- 12G5
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product CXCR4 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
- 别名
- CD184 (CXCR4 产品)
- 背景
- CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2.
- 途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events
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