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CXCR4 抗体 (PE/Dazzle™ 594)

CXCR4 适用: 人 IHC, FACS, IP, BR, CyTOF, St 宿主: 小鼠 Monoclonal 12G5 PE/Dazzle™ 594
产品编号 ABIN2659663
发货至: 中国
  • 抗原 See all CXCR4 抗体
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CXCR4 antibody is conjugated to PE/Dazzle™ 594
    应用范围
    • 109
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    Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR), Cytometry by Time of Flight (CyTOF), Stimulation (St)
    交叉反应
    Chimpanzee, Baboon, Cynomolgus, 猕猴, Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops), Sooty mangabey (Cercocebus atys), Green Monkey (Chlorocebus sabaeus)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions. The solution is free of unconjugated PE/Dazzle™ 594 and unconjugated antibody.
    克隆位点
    12G5
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CXCR4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    别名
    CD184 (CXCR4 产品)
    背景
    CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2.
    途径
    Regulation of Cell Size, CXCR4-mediated Signaling Events
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