Quick Overview for TLR4 /MD2 Complex 抗体 (PE-Cy7) (ABIN2659608)
抗原
TLR4 /MD2 Complex
适用
小鼠
宿主
大鼠
克隆类型
单克隆
标记
PE-Cy7
应用范围
Flow Cytometry (FACS)
克隆位点
MTS510
纯化方法
The antibody was purified by affinity chromatography, and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Protect from prolonged exposure to light. Do not freeze.
储存条件
4 °C
储存方法
The antibody solution should be stored undiluted between 2°C and 8°C.
抗原
TLR4 /MD2 Complex
背景
Toll-like receptors are highly conserved from Drosophila to humans and share structural and functional similarities. They are type I transmembrane signaling receptors which activate the innate immune system in response to pathogen invasion. So far, at least 13 TLR members have been identified. The secretory protein, MD2, associates with cell-surface bound TLR4 (CD284) on monocytes, B cells and T cells. TLR4 has been recognized as critical for host recognition of bacterial LPS in conjunction with MD2.