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- 抗原 See all CD86 抗体
- CD86
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This CD86 antibody is conjugated to PE-Cy7
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应用范围
- Intracellular Flow Cytometry (ICFC)
- 纯化方法
- The antibody was purified by affinity chromatography, and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
- 克隆位点
- PO3
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product CD86 Primary Antibody
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anti-CD86 (CD86) (AA 140-175) antibody
CD86 适用: 人, 小鼠, 大鼠, 犬 FACS, WB, ELISA, IHC (fro), IHC (p), ICC, IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD86 (CD86) (AA 37-272) antibodyCD86 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD86 (CD86) antibodyCD86 适用: 人, 小鼠, 大鼠 FACS, WB, IHC, ELISA, IF, BP, StM, Coat 宿主: 兔 Monoclonal C86-2160R unconjugated Recombinant Antibody
anti-CD86 (CD86) antibodyCD86 适用: 人, 小鼠, 大鼠 FACS, IHC, IF, Func, BP, StM 宿主: 小鼠 Monoclonal BU63 unconjugated
anti-CD86 (CD86) antibodyCD86 适用: 人 FACS, WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal BU63 unconjugated
anti-CD86 (CD86) antibody (FITC)CD86 适用: 人 FACS 宿主: 小鼠 Monoclonal BU63 FITC
anti-CD86 (CD86) antibodyCD86 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-CD86 (CD86) (AA 30-247) antibodyCD86 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CD86 (CD86) antibodyCD86 适用: 人, 小鼠, 大鼠 FACS, IHC, IF, BP, StM 宿主: 小鼠 Monoclonal rC86-1146 unconjugated Recombinant Antibody
anti-CD86 (CD86) antibodyCD86 适用: 人, 小鼠, 大鼠 WB, IHC, IF, BP, StM 宿主: 小鼠 Monoclonal C86-1146 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.2 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- CD86
- 别名
- CD86 (CD86 产品)
- 别名
- B7-2 antibody, B7.2 antibody, B70 antibody, CD28LG2 antibody, LAB72 antibody, B7 antibody, CLS1 antibody, Cd28l2 antibody, ETC-1 antibody, Ly-58 antibody, Ly58 antibody, MB7 antibody, MB7-2 antibody, TS/A-2 antibody, CD86 molecule antibody, CD86 antigen antibody, integrin subunit alpha 2b antibody, CD86 antibody, Cd86 antibody, Itga2b antibody
- 背景
- CD86 is an 80 kD immunoglobulin superfamily member, also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells and astrocytes. CD86 along with CD80 are the ligands of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. The PO3 antibody has been shown to block autoantibody production in vivo and inhibit T cell activation in vitro.
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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