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CD16 抗体 (PE-Cy7)

This anti-CD16 antibody is a 小鼠 单克隆 antibody detecting CD16 in ELISA. Suitable for 人.
产品编号 ABIN2659439
发货至: 中国

Quick Overview for CD16 抗体 (PE-Cy7) (ABIN2659439)

抗原

See all CD16 抗体
CD16

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD16 antibody is conjugated to PE-Cy7

应用范围

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ELISA

克隆位点

3G8
  • 交叉反应

    Chimpanzee, Baboon, Cynomolgus, 猕猴, Marmoset, Capuchin Monkey, Pigtailed Macaque, Sooty mangabey (Cercocebus atys), Squirrel Monkey (Saimiri spec.), Saguinus oedipus

    纯化方法

    The antibody was purified by affinity chromatography, and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD16

    别名

    CD16

    背景

    CD16 is known as low affinity IgG receptor III (FcγRIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans. CD16b (FcγRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95 % homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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