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LY75/DEC-205 抗体 (PE-Cy7)

This anti-LY75/DEC-205 antibody is a 大鼠 单克隆 antibody detecting LY75/DEC-205 in ELISA (Detection). Suitable for 小鼠.
产品编号 ABIN2659172
发货至: 中国

Quick Overview for LY75/DEC-205 抗体 (PE-Cy7) (ABIN2659172)

抗原

See all LY75/DEC-205 (LY75) 抗体
LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

适用

  • 55
  • 31
  • 8
  • 8
  • 2
小鼠

宿主

  • 41
  • 29
  • 7
  • 3
  • 1
  • 1
大鼠

克隆类型

  • 47
  • 32
  • 2
单克隆

标记

  • 43
  • 9
  • 8
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This LY75/DEC-205 antibody is conjugated to PE-Cy7

应用范围

  • 33
  • 27
  • 25
  • 20
  • 15
  • 14
  • 10
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
ELISA (Detection)

克隆位点

NLDC-145
  • 纯化方法

    The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

    别名

    CD205

    背景

    CD205, also known as DEC-205, is a 205 kD integral membrane protein homologous to the macrophage mannose receptor. It is a type I cell surface protein that belong to the C-type lectin family. CD205 is expressed at high levels by dendritic cells and thymic epithelial cells. It is also expressed by a number of other cell types, such as B lymphocytes, macrophages, Langerhans cells, bone marrow stromal cells, granulocytes, epithelial cells of pulmonary airways, and the capillaries of the brain. CD205 is a novel endocytic receptor used by dendritic cells and thymic epithelial cells to direct captured antigens from the extracellular space to specialized antigen processing. It mediates antigen uptake and presentation and cross-presentation to T cells. It has been reported that CD205 acts as a recognition receptor for dying cells, potentially provides an important pathway for the uptake of self-antigen in the intrathymic environment, and is involved in peripheral tolerance. Antibody-mediated antigen-targeting via the DEC-205 receptor increases the efficiency of vaccination for T cell immunity.
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