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Thrombomodulin 抗体 (PE-Cy7)

THBD 适用: 人 FACS 宿主: 小鼠 Monoclonal M80 PE-Cy7
产品编号 ABIN2659097
发货至: 中国
  • 抗原 See all Thrombomodulin (THBD) 抗体
    Thrombomodulin (THBD)
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Thrombomodulin antibody is conjugated to PE-Cy7
    应用范围
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
    克隆位点
    M80
    亚型
    IgG1 kappa
    Top Product
    Discover our top product THBD Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    Thrombomodulin (THBD)
    别名
    CD141 (THBD 产品)
    背景
    CD141 is a 75 kD, single chain, type I membrane glycoprotein also known as thrombomodulin, TM, THRM, THBD, and fetomodulin. CD141 is an important cofactor in the protein C anticoagulant system. After binding to its ligand thrombin, CD141 activates protein C, which degrades clotting factors Va and VIIIa, and as a consequence the amount of thrombin is reduced. CD141 is expressed on macrophages, monocytes, a subpopulation of myeloid dendritic cells, vascular endothelial cells, and keratinocytes. Besides anti-coagulation function, CD141 is also involved in embryonic and atherosclerotic plaque development.
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