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CD8 alpha 抗体 (PE-Cy5)

CD8A 适用: 人 FACS 宿主: 小鼠 Monoclonal RPA-T8 PE-Cy5
产品编号 ABIN2659020
发货至: 中国
  • 抗原 See all CD8 alpha (CD8A) 抗体
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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    小鼠
    克隆类型
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    单克隆
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    This CD8 alpha antibody is conjugated to PE-Cy5
    应用范围
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    Flow Cytometry (FACS)
    交叉反应
    Chimpanzee, Baboon, Cynomolgus, 猕猴, Pigtailed Macaque, Sooty mangabey (Cercocebus atys)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PE/Cy5 under optimal conditions. The solution is free of unconjugated PE/Cy5 and unconjugated antibody.
    克隆位点
    RPA-T8
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD8A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    别名
    CD8a (CD8A 产品)
    背景
    CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation, and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
    途径
    TCR Signaling
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