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ESAM 抗体 (APC)

ESAM 适用: 小鼠 IF, FACS 宿主: 大鼠 Monoclonal 1G8-ESAM APC
产品编号 ABIN2658754
发货至: 中国
  • 抗原 See all ESAM 抗体
    ESAM (Endothelial Cell Adhesion Molecule (ESAM))
    适用
    • 42
    • 23
    • 16
    小鼠
    宿主
    • 56
    • 8
    • 2
    大鼠
    克隆类型
    • 58
    • 8
    单克隆
    标记
    • 27
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This ESAM antibody is conjugated to APC
    应用范围
    • 57
    • 31
    • 15
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
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    Immunofluorescence (IF), Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
    克隆位点
    1G8-ESAM
    亚型
    IgG2a kappa
    Top Product
    Discover our top product ESAM Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    ESAM (Endothelial Cell Adhesion Molecule (ESAM))
    别名
    ESAM (ESAM 产品)
    别名
    ESAM antibody, sc:d0254 antibody, W117m antibody, 2310008D05Rik antibody, Esam1 antibody, endothelial cell adhesion molecule antibody, endothelial cell adhesion molecule a antibody, endothelial cell-specific adhesion molecule antibody, ESAM antibody, esama antibody, Esam antibody
    背景
    Endothelial cell-selective adhesion molecule (ESAM) is a 55-kD membrane protein composed of two extracellular Ig domains, a single transmembrane domain, and a cytoplasmic domain. ESAM is predominantly expressed at endothelial junctions and on platelets, participating in the migration of neutrophils through the vessel wall by influencing endothelial cell contacts. It impacts vascular permeability and extravasation process. Recently, it was reported that ESAM is a novel marker for murine hematopoietic stem cells (HSCs) in fetal liver. ESAM expression is correlated with HSC activity. The ESAMHi population was highly enriched for multipotent myeloid-erythroid progenitors and primitive progenitors with lymphpoietic activity, and exclusively reconstituted long-term lymphohematopoiesis in lethally irradiated recipients.
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