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Macrophage Mannose Receptor 1 抗体 (APC)

This 小鼠 单克隆 antibody specifically detects Macrophage Mannose Receptor 1 in FACS 和 ICFC. It exhibits reactivity toward 人.
产品编号 ABIN2658531
发货至: 中国
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Quick Overview for Macrophage Mannose Receptor 1 抗体 (APC) (ABIN2658531)

抗原

See all Macrophage Mannose Receptor 1 (MRC1) 抗体
Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))

适用

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宿主

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  • 1
小鼠

克隆类型

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  • 46
单克隆

标记

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This Macrophage Mannose Receptor 1 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

克隆位点

15-2
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))

    别名

    CD206

    背景

    Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known as CD206, MRC1, or mannose receptor (MR). It is a pattern recognition receptor (PRR) that belongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, and hepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediates endocytosis and phagocytosis, induces activation of macrophages and antigen presentation, plays an important role in host defense, and provides a link between innate and adaptive immunity.
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