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SIGLEC9 抗体 (APC)

SIGLEC9 适用: 人 FACS, IF, ICFC 宿主: 小鼠 Monoclonal K8 APC
产品编号 ABIN2658391
发货至: 中国
  • 抗原 See all SIGLEC9 抗体
    SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))
    适用
    • 78
    • 12
    • 3
    • 3
    • 1
    • 1
    • 1
    宿主
    • 61
    • 17
    小鼠
    克隆类型
    • 62
    • 16
    单克隆
    标记
    • 33
    • 9
    • 7
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This SIGLEC9 antibody is conjugated to APC
    应用范围
    • 64
    • 35
    • 25
    • 13
    • 10
    • 10
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Intracellular Flow Cytometry (ICFC)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
    克隆位点
    K8
    亚型
    IgG1 kappa
    Top Product
    Discover our top product SIGLEC9 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))
    别名
    Siglec-9 (SIGLEC9 产品)
    别名
    CD329 antibody, CDw329 antibody, FOAP-9 antibody, OBBP-LIKE antibody, siglec-9 antibody, siglec9 antibody, sialic acid binding Ig like lectin 9 antibody, sialic acid-binding immunoglobulin-like lectin 9 antibody, SIGLEC9 antibody
    背景
    Siglecs are cell surface receptors belonging to the immunoglobulin superfamily that recognize sugar antigens. The extracellular domain of siglec-9 contains an IgV region, which binds sialic acid, followed by two IgC regions. Siglec 9 and siglec 6-8,10-12 are CD33 (siglec 3) like siglecs, which have two ITIMs in the cytoplasmic tails, suggesting their functional involvement in signal transduction. It is highly expressed on neutrophils and monocytes, and at lower levels on the subpopulations of T and B lymphocytes and NK cells. Siglec-9 plays a role in negative regulation of T cell activation, and it also affects neutrophil apoptosis.
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