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IL17 Receptor B 抗体 (APC)

The 大鼠 单克隆 anti-IL17 Receptor B antibody is suitable to detect IL17 Receptor B in samples from 小鼠. It has been validated for FACS.
产品编号 ABIN2658344
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL17 Receptor B 抗体 (APC) (ABIN2658344)

抗原

See all IL17 Receptor B (IL17RB) 抗体
IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This IL17 Receptor B antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)

克隆位点

9B10
  • 纯化方法

    The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))

    别名

    IL-17RB

    背景

    IL-17RB, also known as IL17RH1, belongs to the cytokine receptor family. IL-17RB possesses a unique intracellular signaling molecule called SEFIR, and is expressed similarily to fibroblast growth factor genes and IL-17R. It is reported to be expressed on iNKT cells, innate lymphoid cells (ILC), and Th2 cells. It binds IL-17B and IL-17E (IL-25) but not IL-17A or C. Its interaction with IL-25 has a higher affinity than that with IL-17B. Binding of IL-17RB and IL-25/IL-17E induces NF-kB mediated IL-8 production through interaction with TRAF6 and Act1. IL-17RB has been reported to play a role in autoimmune diseases such as rheumatoid arthritis and asthma.
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