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IL17 Receptor B 抗体 (APC)

IL17RB 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 9B10 APC
产品编号 ABIN2658343
发货至: 中国
  • 抗原 See all IL17 Receptor B (IL17RB) 抗体
    IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))
    适用
    • 36
    • 26
    • 22
    • 4
    • 4
    • 4
    小鼠
    宿主
    • 34
    • 5
    • 2
    大鼠
    克隆类型
    • 35
    • 6
    单克隆
    标记
    • 20
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This IL17 Receptor B antibody is conjugated to APC
    应用范围
    • 40
    • 14
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
    克隆位点
    9B10
    亚型
    IgG2a kappa
    Top Product
    Discover our top product IL17RB Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))
    别名
    IL-17RB (IL17RB 产品)
    别名
    IL17RB antibody, CRL4 antibody, EVI27 antibody, IL17BR antibody, IL17RH1 antibody, Evi27 antibody, IL-17ER antibody, IL-17Rh1 antibody, Il17br antibody, interleukin 17 receptor B antibody, IL17RB antibody, Il17rb antibody
    背景
    IL-17RB, also known as IL17RH1, belongs to the cytokine receptor family. IL-17RB possesses a unique intracellular signaling molecule called SEFIR, and is expressed similarily to fibroblast growth factor genes and IL-17R. It is reported to be expressed on iNKT cells, innate lymphoid cells (ILC), and Th2 cells. It binds IL-17B and IL-17E (IL-25) but not IL-17A or C. Its interaction with IL-25 has a higher affinity than that with IL-17B. Binding of IL-17RB and IL-25/IL-17E induces NF-kB mediated IL-8 production through interaction with TRAF6 and Act1. IL-17RB has been reported to play a role in autoimmune diseases such as rheumatoid arthritis and asthma.
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