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CD93 抗体 (APC)

This anti-CD93 antibody is a 大鼠 单克隆 antibody detecting CD93 in IF. Suitable for 小鼠.
产品编号 ABIN2658294
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD93 抗体 (APC) (ABIN2658294)

抗原

See all CD93 抗体
CD93

适用

  • 82
  • 32
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  • 3
小鼠

宿主

  • 54
  • 31
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  • 4
大鼠

克隆类型

  • 54
  • 38
  • 1
单克隆

标记

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  • 2
  • 2
  • 2
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  • 2
  • 2
  • 1
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  • 1
  • 1
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This CD93 antibody is conjugated to APC

应用范围

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Immunofluorescence (IF)

克隆位点

AA4-1
  • 纯化方法

    The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD93

    别名

    CD93

    物质类

    Chemical

    背景

    CD93 is a 130-140 kD C-type lectin-like type I transmembrane protein, also known as complement component 1, q subcomponent (C1qR1), C1qRp collectin receptor (C1qRp), or AA4 antigen. It is a receptor expressed on immature B lymphocytes, hematopoietic progenitors and stem cells in adult bone marrow, fetal liver, and the embryonic yolk sac. CD93 expression levels on splenic immature/transitional B cells is much lower than in bone marrow. It is reinduced during plasma cell differentiation and plays an important role in maintaining plasma cells in bone marrow niches. Immature dendritic cells express CD93 and down-regulate this molecule upon maturation, suggesting they play a role in uptake of particles. CD93 is also expressed on monocytes, macrophages, and endothelial cells. Macrophages from CD93 (-/-) mice had a significant phagocytic defect in the clearance of apoptotic cells in vivo, indicating CD93 may contribute to the in vivo clearance of dying cells. The idea that CD93 binds to C1q remains controversial.
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