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CD8 alpha 抗体 (Alexa Fluor 647)

CD8A 适用: 大鼠 ICFC 宿主: 小鼠 Monoclonal OX-8 Alexa Fluor 647
产品编号 ABIN2657861
发货至: 中国
  • 抗原 See all CD8 alpha (CD8A) 抗体
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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    大鼠
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    小鼠
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    单克隆
    标记
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    This CD8 alpha antibody is conjugated to Alexa Fluor 647
    应用范围
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    Intracellular Flow Cytometry (ICFC)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
    克隆位点
    OX-8
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD8A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    别名
    CD8a (CD8A 产品)
    背景
    CD8a is a 32 kD glycoprotein also known as T8, Lyt2, Ly-2, and CD8α. CD8a is a member of the immunoglobulin superfamily expressed on most thymocytes, subset of mature T cells, most NK cells, macrophages, and some activated CD4+ T cells (not resting). CD8a forms heterodimers with the CD8β chain (CD8b) on the surface of most thymocytes, while mature peripheral T lymphocytes express almost exclusively the CD8 αβ heterodimer. Intestinal intraepithelial lymphocytes express CD8a without CD8b. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck).
    途径
    TCR Signaling
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