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IL18R1 抗体 (Alexa Fluor 647)

IL18R1 适用: 小鼠 WB, FACS 宿主: 大鼠 Monoclonal BG-IL18Ra Alexa Fluor 647
产品编号 ABIN2657695
发货至: 中国
  • 抗原 See all IL18R1 抗体
    IL18R1 (Interleukin 18 Receptor 1 (IL18R1))
    适用
    • 73
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    小鼠
    宿主
    • 62
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    大鼠
    克隆类型
    • 63
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    单克隆
    标记
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    This IL18R1 antibody is conjugated to Alexa Fluor 647
    应用范围
    • 59
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    Western Blotting (WB), Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
    克隆位点
    BG-IL18Ra
    亚型
    IgG1
    Top Product
    Discover our top product IL18R1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原
    IL18R1 (Interleukin 18 Receptor 1 (IL18R1))
    别名
    CD218a (IL18R1 产品)
    别名
    CD218a antibody, CDw218a antibody, IL-1Rrp antibody, IL18RA antibody, IL1RRP antibody, IL-1R9 antibody, IL1R9 antibody, IL1RAPL-2 antibody, TIGIRR-1 antibody, Il18ralpha antibody, Il1rrp antibody, IL-18Ra antibody, IL18R1 antibody, interleukin 18 receptor 1 antibody, interleukin 1 receptor accessory protein like 2 antibody, IL18R1 antibody, IL1RAPL2 antibody, Il18r1 antibody
    背景
    The IL-18 receptor (IL-18R) complex is composed of two known chains, IL-18 receptor α (IL-18Rα) and IL-18 receptor β (IL-18Rβ). IL-18Rα (IL-1R5) is an IL-1 receptor super family member. It was originally described as IL-1 receptor-related protein (IL-1Rrp) because of its homology with the IL-1/Toll receptor family. IL-18Rα is the extracellular binding domain of the IL-18 receptor complex. It is expressed on the majority of peripheral CD4+ T cells, Th1 cells, and reciprocally repressed during Th2 development. The expression of IL-18Rα is induced by an IL-12/Stat4 pathway and inhibited by IL-4/Stat6 pathway. Binding of IL-18Rα together with IL-18β to proinflammatory cytokine IL-18 plays an important role in innate and autoimmune responses.
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