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IL18R1 抗体 (Alexa Fluor 647)

The 大鼠 单克隆 anti-IL18R1 antibody is suitable to detect IL18R1 in samples from 小鼠. It has been validated for WB 和 FACS.
产品编号 ABIN2657695
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL18R1 抗体 (Alexa Fluor 647) (ABIN2657695)

抗原

See all IL18R1 抗体
IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This IL18R1 antibody is conjugated to Alexa Fluor 647

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

BG-IL18Ra
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原

    IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

    别名

    CD218a

    背景

    The IL-18 receptor (IL-18R) complex is composed of two known chains, IL-18 receptor α (IL-18Rα) and IL-18 receptor β (IL-18Rβ). IL-18Rα (IL-1R5) is an IL-1 receptor super family member. It was originally described as IL-1 receptor-related protein (IL-1Rrp) because of its homology with the IL-1/Toll receptor family. IL-18Rα is the extracellular binding domain of the IL-18 receptor complex. It is expressed on the majority of peripheral CD4+ T cells, Th1 cells, and reciprocally repressed during Th2 development. The expression of IL-18Rα is induced by an IL-12/Stat4 pathway and inhibited by IL-4/Stat6 pathway. Binding of IL-18Rα together with IL-18β to proinflammatory cytokine IL-18 plays an important role in innate and autoimmune responses.
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