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IL17F 抗体 (Alexa Fluor 488)

IL17F 适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 9D3-1C8 Alexa Fluor 488
产品编号 ABIN2657542
发货至: 中国
  • 抗原 See all IL17F 抗体
    IL17F (Interleukin 17F (IL17F))
    适用
    • 77
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    小鼠
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This IL17F antibody is conjugated to Alexa Fluor 488
    应用范围
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.
    克隆位点
    9D3-1C8
    亚型
    IgG1 kappa
    Top Product
    Discover our top product IL17F Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原
    IL17F (Interleukin 17F (IL17F))
    别名
    IL-17F (IL17F 产品)
    别名
    CANDF6 antibody, IL-17F antibody, ML-1 antibody, ML1 antibody, C87042 antibody, IL17F antibody, interleukin 17F antibody, IL17F antibody, Il17f antibody
    背景
    Interleukin 17F (IL-17F) is a 37 kD IL-17 family member. The IL-17 family consists of six members including IL-17 (also called IL-17A), IL-17B, IL-17C, IL-17D, IL-17E (also called IL-25), and IL-17F. IL-17F shares the strongest similarity to IL-17A and forms a homodimer or heterodimer with IL-17A. It is produced by Th17 cells, mast cells, basophils, and epithelial cells. IL-17F is an important regulator of inflammatory responses. It is involved in host defense against mucoepithelial infection by Staphylococcus aureus and Citrobacter rodentium. Over expression of IL-17F gene in the airway of mice is associated with airway neutrophilia, the induction of many cytokines, an increase in airway hyperreactivity, and mucus hyper-secretion. IL-17F is also involved in cancer immunity and autoimmune responses. IL-17F, like IL-17A, depends on IL-17R for its signaling in vitro and in vivo. P38 MAPK, ERK1/2, Act1 (NF-KB activator protein 1), and TRAF6 are involved in IL-17F signaling.
    途径
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
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