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IL17F 抗体 (Alexa Fluor 488)

This anti-IL17F antibody is a 小鼠 单克隆 antibody detecting IL17F in FACS. Suitable for 小鼠.
产品编号 ABIN2657542
发货至: 中国

Quick Overview for IL17F 抗体 (Alexa Fluor 488) (ABIN2657542)

抗原

See all IL17F 抗体
IL17F (Interleukin 17F (IL17F))

适用

  • 87
  • 32
  • 20
小鼠

宿主

  • 89
  • 26
  • 2
小鼠

克隆类型

  • 92
  • 24
  • 1
单克隆

标记

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  • 1
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This IL17F antibody is conjugated to Alexa Fluor 488

应用范围

  • 84
  • 55
  • 35
  • 21
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  • 12
  • 8
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Flow Cytometry (FACS)

克隆位点

9D3-1C8
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原

    IL17F (Interleukin 17F (IL17F))

    别名

    IL-17F

    背景

    Interleukin 17F (IL-17F) is a 37 kD IL-17 family member. The IL-17 family consists of six members including IL-17 (also called IL-17A), IL-17B, IL-17C, IL-17D, IL-17E (also called IL-25), and IL-17F. IL-17F shares the strongest similarity to IL-17A and forms a homodimer or heterodimer with IL-17A. It is produced by Th17 cells, mast cells, basophils, and epithelial cells. IL-17F is an important regulator of inflammatory responses. It is involved in host defense against mucoepithelial infection by Staphylococcus aureus and Citrobacter rodentium. Over expression of IL-17F gene in the airway of mice is associated with airway neutrophilia, the induction of many cytokines, an increase in airway hyperreactivity, and mucus hyper-secretion. IL-17F is also involved in cancer immunity and autoimmune responses. IL-17F, like IL-17A, depends on IL-17R for its signaling in vitro and in vivo. P38 MAPK, ERK1/2, Act1 (NF-KB activator protein 1), and TRAF6 are involved in IL-17F signaling.

    途径

    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
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