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INPP5D 抗体 (Alexa Fluor 647)

INPP5D 适用: 人, 小鼠 FACS, IHC 宿主: 小鼠 Monoclonal P1C1-A5 Alexa Fluor 647
产品编号 ABIN2657227
发货至: 中国
  • 抗原 See all INPP5D 抗体
    INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
    适用
    • 83
    • 58
    • 37
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 82
    • 2
    小鼠
    克隆类型
    • 71
    • 13
    单克隆
    标记
    • 33
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
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    This INPP5D antibody is conjugated to Alexa Fluor 647
    应用范围
    • 60
    • 20
    • 16
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
    克隆位点
    P1C1-A5
    亚型
    IgG1 kappa
    Top Product
    Discover our top product INPP5D Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原
    INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
    别名
    SHIP-1 (INPP5D 产品)
    别名
    INPP5D antibody, 256.t00004 antibody, 13.t00027 antibody, ship antibody, ship1 antibody, AI323613 antibody, SHIP antibody, SHIP-1 antibody, SHIP1 antibody, s-SHIP antibody, SIP-145 antibody, hp51CN antibody, inositol polyphosphate-5-phosphatase D antibody, phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 antibody, inositol polyphosphate 5-phosphatase antibody, inositol polyphosphate-5-phosphatase D L homeolog antibody, INPP5D antibody, LOC100446045 antibody, inpp5d antibody, EHI_159880 antibody, EHI_153490 antibody, inpp5d.L antibody, LOC100380693 antibody, Inpp5d antibody
    背景
    SH2-containing inositol phosphatase 1 (SHIP1) is a hematopoietic phosphatase that hydrolyzes key signaling lipid PI(3,4,5)P(3) to PI(3,4)P(2). SHIP-1 is located in the cytoplasm and is recruited to the cell surface upon receptor ligation. It plays critical roles in hematopoietic cell proliferation, activation, differentiation, and survival by regulating PI3K and Akt pathways. Aberrant regulation of PI3K signaling can induce autoimmune diseases and cancer formation.
    途径
    TCR Signaling, BCR Signaling, Warburg Effect
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