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IL17 Receptor B 抗体 (Alexa Fluor 647)

This anti-IL17 Receptor B antibody is a 大鼠 单克隆 antibody detecting IL17 Receptor B in FACS. Suitable for 小鼠.
产品编号 ABIN2657212
发货至: 中国
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Quick Overview for IL17 Receptor B 抗体 (Alexa Fluor 647) (ABIN2657212)

抗原

See all IL17 Receptor B (IL17RB) 抗体
IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))

适用

  • 27
  • 8
  • 4
小鼠

宿主

  • 25
  • 5
  • 2
  • 1
  • 1
大鼠

克隆类型

  • 26
  • 8
单克隆

标记

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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This IL17 Receptor B antibody is conjugated to Alexa Fluor 647

应用范围

  • 25
  • 13
  • 13
  • 8
  • 6
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  • 2
  • 1
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Flow Cytometry (FACS)

克隆位点

9B10
  • 纯化方法

    The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原

    IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))

    别名

    IL-17RB

    背景

    IL-17RB, also known as IL17RH1, belongs to the cytokine receptor family. IL-17RB possesses a unique intracellular signaling molecule called SEFIR, and is expressed similarily to fibroblast growth factor genes and IL-17R. It is reported to be expressed on iNKT cells, innate lymphoid cells (ILC), and Th2 cells. It binds IL-17B and IL-17E (IL-25) but not IL-17A or C. Its interaction with IL-25 has a higher affinity than that with IL-17B. Binding of IL-17RB and IL-25/IL-17E induces NF-kB mediated IL-8 production through interaction with TRAF6 and Act1. IL-17RB has been reported to play a role in autoimmune diseases such as rheumatoid arthritis and asthma.
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