Cutaneous Lymphocyte Antigen 抗体 (Alexa Fluor 647)
This anti- antibody is a 大鼠 单克隆 antibody detecting in FACS. Suitable for 人 和 小鼠.
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Quick Overview for Cutaneous Lymphocyte Antigen 抗体 (Alexa Fluor 647) (ABIN2657192)
抗原
Cutaneous Lymphocyte Antigen
适用
人, 小鼠
宿主
大鼠
克隆类型
单克隆
标记
Alexa Fluor 647
应用范围
Flow Cytometry (FACS)
克隆位点
HECA-452
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纯化方法
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
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亚型
- IgM kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from prolonged exposure to light. Do not freeze.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C
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- Cutaneous Lymphocyte Antigen
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背景
- Cutaneous lymphocyte antigen (CLA) is a 140 kD homodimer protein recognized by a unique mAb, HECA-452. It is expressed on T cells in skin, subsets of peripheral blood memory T cells, NK cells, memory B cells and dendritic cells as well as on monocytes, granulocytes, and activated endothelial cells. CLA is a carbohydrate epitope of sialic acid and fucose-modified P-selectin glycoprotein ligand-1 (PSGL-1), a surface glycoprotein expressed on the majority of peripheral blood leukocytes. CLA is a ligand for E-selectin, P-selectin, and L-selectin. It plays a role in memory lymphocyte homing, tethering, and rolling.
抗原
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