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Thrombomodulin 抗体 (APC)

This APC-conjugated 小鼠 单克隆 anti-Thrombomodulin antibody (Clone M80) specifically detects Thrombomodulin in BCA. The antibody is reactive with 人 samples.
产品编号 ABIN2656921
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Thrombomodulin 抗体 (APC) (ABIN2656921)

抗原

See all Thrombomodulin (THBD) 抗体
Thrombomodulin (THBD)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Thrombomodulin antibody is conjugated to APC

应用范围

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Biochemical Assay (BCA)

克隆位点

M80
  • 纯化方法

    The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原

    Thrombomodulin (THBD)

    别名

    CD141

    背景

    CD141 is a 75 kD, single chain, type I membrane glycoprotein also known as thrombomodulin, TM, THRM, THBD, and fetomodulin. CD141 is an important cofactor in the protein C anticoagulant system. After binding to its ligand thrombin, CD141 activates protein C, which degrades clotting factors Va and VIIIa, and as a consequence the amount of thrombin is reduced. CD141 is expressed on macrophages, monocytes, a subpopulation of myeloid dendritic cells, vascular endothelial cells, and keratinocytes. Besides anti-coagulation function, CD141 is also involved in embryonic and atherosclerotic plaque development.
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