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- 抗原 See all VTCN1 抗体
- VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))
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适用
- 小鼠
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宿主
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Armenian Hamster
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克隆类型
- 单克隆
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标记
- This VTCN1 antibody is conjugated to APC
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
- 克隆位点
- HMH4-5G1
- 亚型
- IgG
- Top Product
- Discover our top product VTCN1 Primary Antibody
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anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 50-100) antibody
VTCN1 适用: 人 ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 34-147) antibodyVTCN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) antibodyVTCN1 适用: 人 WB, ELISA, IHC, FACS, IF, Coat, StM 宿主: 小鼠 Monoclonal B7H4-1788 unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 153-241) antibodyVTCN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) antibodyVTCN1 适用: 人 ELISA, IHC, FACS, IF, Coat, StM 宿主: 兔 Monoclonal B7H4-2652R unconjugated Recombinant Antibody
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (Internal Region) antibodyVerified VTCN1 适用: 人 WB, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 25-259) antibodyVTCN1 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 3A9C12 unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 26-258) antibodyVTCN1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 34-147) antibodyVTCN1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D4 unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 26-258) antibodyVTCN1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.2 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C
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- 抗原
- VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))
- 别名
- B7-H4 B7S1 (VTCN1 产品)
- 别名
- B7h4 antibody, B7s1 antibody, B7x antibody, BC032925 antibody, B7-H4 antibody, B7H4 antibody, B7S1 antibody, B7X antibody, B7h.5 antibody, PRO1291 antibody, VCTN1 antibody, RGD1311204 antibody, V set domain containing T cell activation inhibitor 1 L homeolog antibody, V-set domain containing T cell activation inhibitor 1 antibody, V-set domain containing T-cell activation inhibitor 1 antibody, V set domain containing T cell activation inhibitor 1 antibody, vtcn1.L antibody, VTCN1 antibody, vtcn1 antibody, Vtcn1 antibody
- 背景
- B7-H4 is a newly discovered B7 family member that negatively regulates T cell immunity. In vitro, B7-H4 inhibits CD4+ and CD8+ T cell proliferation, cytokine production, and generation of alloreactive cytotoxic T-cells (CTLs). In vivo, blockage of endogenous B7-H4 by specific monoclonal antibodies promotes T cell responses. A new reported function of B7-H4 is as an important negative regulator of innate immunity through growth inhibition of neutrophils. It has been reported that B7-H4 is not constitutively expressed on peripheral tissues but can be induced to express on T cells, B cells, macrophages, and dendritic cells. B7-H4 is expressed on some tumor cancer cells. The role of B7-H4 in tumor progression may be to transform precancerous cells and then protect them from immunosurveillance. Although B- and T-lymphocyte attenuator (BTLA) was proposed to be the receptor for B7-H4, further studies are needed to identify the inhibitory receptor of B7-H4.
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