VTCN1 抗体 (APC)
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北京 101111
Quick Overview for VTCN1 抗体 (APC) (ABIN2656873)
抗原
See all VTCN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
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亚型
- IgG
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anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 50-100) antibody
VTCN1 适用: 人 ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 34-147) antibodyVTCN1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) antibodyVTCN1 适用: 人 WB, IHC, ELISA, FACS, IF, Coat, StM 宿主: 小鼠 Monoclonal B7H4-1788 unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 153-241) antibodyVTCN1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (Internal Region) antibodyVerified VTCN1 适用: 人 WB, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) antibodyVTCN1 适用: 人 IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal H74 unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) antibodyVTCN1 适用: 人 IHC, ELISA, FACS, IF, Coat, StM 宿主: 兔 Monoclonal B7H4-2652R unconjugated Recombinant Antibody
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 25-259) antibodyVTCN1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3A9C12 unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 26-258) antibodyVTCN1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 34-147) antibodyVTCN1 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal 6# unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from prolonged exposure to light. Do not freeze.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C
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- VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))
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别名
- B7-H4 B7S1
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背景
- B7-H4 is a newly discovered B7 family member that negatively regulates T cell immunity. In vitro, B7-H4 inhibits CD4+ and CD8+ T cell proliferation, cytokine production, and generation of alloreactive cytotoxic T-cells (CTLs). In vivo, blockage of endogenous B7-H4 by specific monoclonal antibodies promotes T cell responses. A new reported function of B7-H4 is as an important negative regulator of innate immunity through growth inhibition of neutrophils. It has been reported that B7-H4 is not constitutively expressed on peripheral tissues but can be induced to express on T cells, B cells, macrophages, and dendritic cells. B7-H4 is expressed on some tumor cancer cells. The role of B7-H4 in tumor progression may be to transform precancerous cells and then protect them from immunosurveillance. Although B- and T-lymphocyte attenuator (BTLA) was proposed to be the receptor for B7-H4, further studies are needed to identify the inhibitory receptor of B7-H4.
抗原
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