MMP3 抗体
(9 references)Quick Overview for MMP3 抗体 (ABIN265531)
抗原
See all MMP3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of MMP-3 protein. (region surrounding Ser453)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen.
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anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 248-477) antibody
MMP3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 363-477) antibodyMMP3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A3 unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 278-450) antibodyMMP3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 1-477) antibodyMMP3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) antibodyMMP3 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 401-477) antibodyMMP3 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 100-477) antibodyMMP3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 22-131) antibodyMMP3 适用: 人 ELISA, IP 宿主: 小鼠 Monoclonal 4C11 unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (C-Term) antibodyMMP3 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) antibodyMMP3 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4F10 unconjugated
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应用备注
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ELISA: 1/10000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Multidrug resistance protein 3 loss promotes tumor formation by inducing senescence escape." in: Oncogene, Vol. 35, Issue 12, pp. 1596-601, (2016) (PubMed).
: "Oxidation of structural cysteine residues in thioredoxin 1 by aromatic arsenicals enhances cancer cell cytotoxicity caused by the inhibition of thioredoxin reductase 1." in: Free radical biology & medicine, Vol. 89, pp. 192-200, (2016) (PubMed).
: "Temporary inductions of matrix metalloprotease-3 (MMP-3) expression and cell apoptosis are associated with tendon degeneration or rupture after corticosteroid injection." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 32, Issue 10, pp. 1297-304, (2014) (PubMed).
: "Effects of chronic sleep deprivation on the extracellular signal-regulated kinase pathway in the temporomandibular joint of rats." in: PLoS ONE, Vol. 9, Issue 9, pp. e107544, (2014) (PubMed).
: "Effect of infliximab on the healing of intestinal anastomosis. An experimental study in rats." in: International journal of surgery (London, England), Vol. 12, Issue 9, pp. 969-75, (2014) (PubMed).
: "OSR1-sensitive small intestinal Na+ transport." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 303, Issue 11, pp. G1212-9, (2012) (PubMed).
: "Proteolytic release of the receptor for advanced glycation end products from in vitro and in situ alveolar epithelial cells." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 300, Issue 4, pp. L516-25, (2011) (PubMed).
: "p28GANK overexpression accelerates hepatocellular carcinoma invasiveness and metastasis via phosphoinositol 3-kinase/AKT/hypoxia-inducible factor-1α pathways." in: Hepatology (Baltimore, Md.), Vol. 53, Issue 1, pp. 181-92, (2011) (PubMed).
: "Local hyperthermia could induce antiviral activity by endogenous interferon-dependent pathway in condyloma acuminata." in: Antiviral research, Vol. 88, Issue 2, pp. 187-92, (2010) (PubMed).
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: "Multidrug resistance protein 3 loss promotes tumor formation by inducing senescence escape." in: Oncogene, Vol. 35, Issue 12, pp. 1596-601, (2016) (PubMed).
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- MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))
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别名
- MMP-3
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背景
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP3 is an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. MMP3 is reported to be implicated in rheumatoid arthritis and some forms of cancer.Synonyms: MMP3, Matrix metalloproteinase-3, SL-1, STMY1, Stromelysin-1, Transin-1
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分子量
- approx. 53 kDa
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基因ID
- 4314
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NCBI登录号
- NP_002413
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UniProt
- P08254
抗原
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