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Matrix Metallopeptidase 23 (MMP23) 抗体

MMP23 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265530
发货至: 中国
  • 抗原 See all Matrix Metallopeptidase 23 (MMP23) 抗体
    Matrix Metallopeptidase 23 (MMP23)
    适用
    • 36
    • 12
    • 12
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 36
    克隆类型
    • 36
    多克隆
    标记
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 13
    • 13
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of MMP-23 protein. (region surrounding Val371)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product MMP23 Primary Antibody
  • 应用备注
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    Matrix Metallopeptidase 23 (MMP23)
    别名
    MMP-23 (MMP23 产品)
    别名
    CA-MMP antibody, matrix metallopeptidase 23 antibody, Mmp23 antibody
    背景
    Matrix metalloproteinases (MMPs) are highly homologous Zn2+ endopeptidases involved in extracellular matrix breakdown. MMP mediated extracellular remodeling occurs in normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, including arthritis and metastasis. MMP-23 exhibits sequence similarity with most MMPs, but displays a difference in domain structure. The MMP-23 protein contains prepro-, catalytic, cysteine-rich, Interleukin-1 receptor-related and proline-rich domains. Lacking a recognizable signal sequence, MMP-23 has a short prodomain. In addition, MMP-23 contains a single cysteine residue that can be part of the cysteine-switch mechanism operation for maintaining enzyme latency. MMP-23 is a membrane-anchored glycoprotein with type II topology. Subcellular localization is predominantly perinuclear.Synonyms: Femalysin, MIFR-1, MMP21, MMP22, MMP23A, MMP23B, Matrix metallopeptidase 21, Matrix metalloprotease 22, Matrix metalloproteinase-23
    分子量
    approx. 44 kDa
    基因ID
    8510
    NCBI登录号
    NP_008914
    UniProt
    O75900
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