Matrix Metallopeptidase 23 (MMP23) 抗体
The 兔 多克隆 anti-Matrix Metallopeptidase 23 antibody (ABIN265530) specifically detects Matrix Metallopeptidase 23 in WB.
The antibody is reactive with 人, 小鼠 和 大鼠 samples.
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产品编号 ABIN265530
发货至:
中国
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Quick Overview for Matrix Metallopeptidase 23 (MMP23) 抗体 (ABIN265530)
抗原
See all Matrix Metallopeptidase 23 (MMP23) 抗体
Matrix Metallopeptidase 23 (MMP23)
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB)
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特异性
- This antibody detects endogenous levels of MMP-23 protein. (region surrounding Val371)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Matrix Metallopeptidase 23 (MMP23) (AA 281-380) antibody
MMP23 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 23 (MMP23) (cleaved), (Tyr79) antibodyMMP23 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- Matrix Metallopeptidase 23 (MMP23)
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别名
- MMP-23
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背景
- Matrix metalloproteinases (MMPs) are highly homologous Zn2+ endopeptidases involved in extracellular matrix breakdown. MMP mediated extracellular remodeling occurs in normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, including arthritis and metastasis. MMP-23 exhibits sequence similarity with most MMPs, but displays a difference in domain structure. The MMP-23 protein contains prepro-, catalytic, cysteine-rich, Interleukin-1 receptor-related and proline-rich domains. Lacking a recognizable signal sequence, MMP-23 has a short prodomain. In addition, MMP-23 contains a single cysteine residue that can be part of the cysteine-switch mechanism operation for maintaining enzyme latency. MMP-23 is a membrane-anchored glycoprotein with type II topology. Subcellular localization is predominantly perinuclear.Synonyms: Femalysin, MIFR-1, MMP21, MMP22, MMP23A, MMP23B, Matrix metallopeptidase 21, Matrix metalloprotease 22, Matrix metalloproteinase-23
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分子量
- approx. 44 kDa
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基因ID
- 8510
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NCBI登录号
- NP_008914
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UniProt
- O75900
抗原
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