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MMP15 抗体

MMP15 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265526
发货至: 中国
  • 抗原 See all MMP15 抗体
    MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))
    适用
    • 56
    • 39
    • 21
    • 4
    • 4
    • 4
    • 1
    人, 小鼠
    宿主
    • 58
    • 2
    克隆类型
    • 58
    • 2
    多克隆
    标记
    • 25
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This MMP15 antibody is un-conjugated
    应用范围
    • 59
    • 32
    • 25
    • 10
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of MMP-15 protein. (region surrounding Leu646)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product MMP15 Primary Antibody
  • 应用备注
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))
    别名
    MMP-15 (MMP15 产品)
    别名
    AI503551 antibody, MT2-MMP antibody, MTMMP2 antibody, SMCP-2 antibody, matrix metallopeptidase 15 antibody, MMP15 antibody, Mmp15 antibody
    背景
    The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is downregulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression.Synonyms: MMP15, MT-MMP 2, MT2-MMP, MT2MMP, MTMMP2, Matrix metalloproteinase-15, Membrane-type matrix metalloproteinase 2, Membrane-type-2 matrix metalloproteinase, SMCP-2
    分子量
    approx. 80 kDa
    基因ID
    4324
    NCBI登录号
    NP_002419
    UniProt
    P51511
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