MMP1 抗体
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北京 101111
Quick Overview for MMP1 抗体 (ABIN265522)
抗原
See all MMP1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of MMP-1 protein. (region surrounding His440)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) antibody
MMP1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 1-469) antibodyMMP1 适用: 人 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) antibodyMMP1 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6A5 unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 169-464) antibodyMMP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 20-280) antibodyMMP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (N-Term) antibodyMMP1 适用: 人, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 1-469) antibodyMMP1 适用: 人 WB, IHC (p), PLA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (C-Term) antibodyMMP1 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 317-347) antibodyMMP1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 98-275) antibodyMMP1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
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别名
- MMP-1
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背景
- The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is downregulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression.Synonyms: CLG, Fibroblast collagenase, Interstitial collagenase, MMP1, Matrix metalloproteinase-1
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分子量
- approx. 54 kDa
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基因ID
- 4312
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NCBI登录号
- NP_002412
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UniProt
- P03956
抗原
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