KRT17 抗体
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北京 101111
Quick Overview for KRT17 抗体 (ABIN265496)
抗原
See all KRT17 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Keratin 17/36 protein. (region surrounding Val412)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Keratin 17 (KRT17) antibody
KRT17 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) (AA 252-393) antibodyKRT17 适用: 人 WB, IHC, ICC, FACS, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) (AA 1-432) antibodyKRT17 适用: 人 WB, IF, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 2D4-1G9 unconjugated
anti-Keratin 17 (KRT17) antibodyKRT17 适用: 人, 大鼠 WB, IHC, ICC, FACS, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal E3 unconjugated
anti-Keratin 17 (KRT17) (AA 133-432) antibodyKRT17 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) antibodyKD Validated KRT17 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB6535 unconjugated Recombinant Antibody
anti-Keratin 17 (KRT17) antibodyKRT17 适用: 人, 大鼠, Cow, Pig, 山羊 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal SPM560 unconjugated
anti-Keratin 17 (KRT17) (C-Term) antibodyKRT17 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) antibodyKRT17 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 3B12 unconjugated
anti-Keratin 17 (KRT17) antibodyKRT17 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- KRT17 (Keratin 17 (KRT17))
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别名
- Cytokeratin 17
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背景
- Cytokeratin 17 is a member of the Cytokeratin subfamily of intermediate filament proteins (IFPs). It is unique in that it is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Cytokeratin 17 contains 432 amino acids and is expressed in the nail bed, hair follicle, sebaceous glands and other epidermal appendages. Cytokeratin 17 functions to regulate cell growth and size through its interactions with the adaptor protein 14-3-3-sigma to mediate protein synthesis. Mutations in the gene encoding for Cytokeratin 17 lead to depressed protein translation and smaller sized skin keratinocytes, corresponding to decreased Akt/mTOR signaling activity. Cytokeratin 17 may be a useful marker for cervical stem cell identification, squamous cell carcinoma of the larynx, respiratory syncytial virus and transitional cell carcinomas of the human urinary tract.Synonyms: CK17, Cytokeratin-17, K17, KRT17, Keratin 17, Keratin type I cytoskeletal 17, Keratin-17
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分子量
- approx. 50 kDa
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基因ID
- 3872
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NCBI登录号
- NP_000413
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UniProt
- Q04695
抗原
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