KRT16 抗体
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北京 101111
Quick Overview for KRT16 抗体 (ABIN265495)
抗原
See all KRT16 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Cytokeratin 16 protein. (region surroundign Ser451)
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交叉反应 （详细）
- Species reactivity (expected):Mouse and RatSpecies reactivity (tested):Human.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Keratin 16 (KRT16) (AA 190-430) antibody
KRT16 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 16 (KRT16) antibodyKRT16 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 1A4 unconjugated
anti-Keratin 16 (KRT16) (AA 265-333) antibodyKRT16 适用: 人 IHC, WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 16 (KRT16) (AA 117-419) antibodyKRT16 适用: 人 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 16 (KRT16) antibodyKRT16 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Keratin 16 (KRT16) (AA 1-473) antibodyKRT16 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Keratin 16 (KRT16) (AA 301-398) antibodyKRT16 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Keratin 16 (KRT16) (C-Term) antibodyKRT16 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 16 (KRT16) antibodyKRT16 适用: 人 宿主: 小鼠 Monoclonal LL025 unconjugated
anti-Keratin 16 (KRT16) (AA 251-300) antibodyKRT16 适用: 人, 小鼠, 大鼠, 马 IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Effect of advanced oxidation protein products on articular cartilage and synovium in a rabbit osteoarthritis model." in: Orthopaedic surgery, Vol. 7, Issue 2, pp. 161-7, (2016) (PubMed).
: "Interferon-? regulates the function of mesenchymal stem cells from oral lichen planus via indoleamine 2,3-dioxygenase activity." in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, Vol. 44, Issue 1, pp. 15-27, (2015) (PubMed).
: "Heparin/heparan sulfate/CD44-v3 enhances cell migration in term placenta-derived immortalized human trophoblast cells." in: Biology of reproduction, Vol. 86, Issue 5, pp. 134, 1-8, (2012) (PubMed).
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: "Effect of advanced oxidation protein products on articular cartilage and synovium in a rabbit osteoarthritis model." in: Orthopaedic surgery, Vol. 7, Issue 2, pp. 161-7, (2016) (PubMed).
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- KRT16 (Keratin 16 (KRT16))
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别名
- Cytokeratin 16
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背景
- Keratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10 % of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating. Two cytokeratins, 6 and 16, are expressed when keratincytes are undergoing rapid turnover in various pathological states, wound healing, psoriasis and some carcinomasSynonyms: CK16, Cytokeratin-16, K16, KRT16, KRT16A, Keratin 16, Keratin type I cytoskeletal 16, Keratin-16
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分子量
- approx. 52 kDa
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基因ID
- 3868
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NCBI登录号
- NP_005548
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UniProt
- P08779
抗原
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