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JunD 抗体

This anti-JunD antibody is a 兔 多克隆 antibody detecting JunD in WB, IP, IHC (p) 和 EIA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN265491
发货至: 中国

Quick Overview for JunD 抗体 (ABIN265491)

抗原

See all JunD (JUND) 抗体
JunD (JUND) (Jun D Proto-Oncogene (JUND))

适用

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人, 大鼠, 小鼠

宿主

  • 111
  • 1
  • 1
  • 1

克隆类型

  • 100
  • 14
多克隆

标记

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This JunD antibody is un-conjugated

应用范围

  • 88
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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of JunD protein. (region surrounding Val249)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen
  • 应用备注

    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IP: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    JunD (JUND) (Jun D Proto-Oncogene (JUND))

    别名

    Jun-D

    背景

    The activator protein-1 (AP-1) transcription factor consists of either Jun/Jun homodimers or Fos/Jun heterodimeric complexes. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Jun B and Jun D have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family. Studies suggest that the two forms of Jun D may be due to internal initiation of translation.Synonyms: JUND, Transcription factor jun-D

    分子量

    approx. 35.0 kDa

    基因ID

    3727

    NCBI登录号

    NP_005345

    UniProt

    P17535
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