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JunB 抗体

This anti-JunB antibody is a 兔 多克隆 antibody detecting JunB in WB, IP, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN265489
发货至: 中国

Quick Overview for JunB 抗体 (ABIN265489)

抗原

See all JunB (JUNB) 抗体
JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

适用

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人, 小鼠

宿主

  • 116
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克隆类型

  • 107
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多克隆

标记

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This JunB antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of JunB protein. (region surrounding Asp253)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen
  • 应用备注

    ELISA: 1: 10000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IP: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

    别名

    Jun-B

    背景

    The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein along with c-Fos is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes, Jun B and Jun D have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in ranscriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.Synonyms: JUNB, Transcription factor jun-B

    分子量

    approx. 43 kDa

    基因ID

    3726

    NCBI登录号

    NP_002220

    UniProt

    P17275
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