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PRAF2 抗体

PRAF2 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265488
发货至: 中国
  • 抗原 See all PRAF2 抗体
    PRAF2 (PRA1 Domain Family, Member 2 (PRAF2))
    适用
    • 13
    • 12
    • 12
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 13
    克隆类型
    • 13
    多克隆
    标记
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRAF2 antibody is un-conjugated
    应用范围
    • 6
    • 4
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of JM4/PRAF2 protein. (region surrounding Leu166)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product PRAF2 Primary Antibody
  • 应用备注
    ELISA: 1: 10000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PRAF2 (PRA1 Domain Family, Member 2 (PRAF2))
    别名
    JM4 / PRAF2 (PRAF2 产品)
    别名
    AA986329 antibody, C78013 antibody, DXImx39e antibody, JM4 antibody, Sfc20 antibody, PRA1 domain family member 2 antibody, PRA1 domain family 2 antibody, PRAF2 antibody, Praf2 antibody
    背景
    JM4 (Jena-Muenchen 4), also known as PRAF2 (PRA1 domain family, member 2), is a 178 amino acid endosomal multi-pass membrane protein involved in vesicular trafficking and Endoplasmic reticulum/Golgi transport. As a member of the PRA1 family, JM4 contains four putative transmembrane (TM) domains, interacts with the CC chemokine receptor 5 (CCR5) and colocalizes with Calnexin in the ER and mannose 6-phosphate receptor (CD-MPR) in the Golgi apparatus. While ubiquitously expressed, JM4 has been found at high levels in small intestine, lung, pancreas, spleen, Purkinje cells of the cerebellum and in neuronal cells of the hippocampus, cerebral cortex and lateral ventricles of the brain. JM4 plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis and has been implicated in human cancer.Synonyms: PRA1 family protein 2
    分子量
    approx. 20 kDa
    基因ID
    11230
    NCBI登录号
    NP_009144
    UniProt
    O60831
    途径
    Dicarboxylic Acid Transport
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