Integrin beta 5 抗体
Quick Overview for Integrin beta 5 抗体 (ABIN265481)
抗原
See all Integrin beta 5 (ITGB5) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody antibody detects endogenous levels of Integrin beta5 protein. (region surrounding Val746)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Integrin beta 5 (ITGB5) (AA 421-516) antibody
ITGB5 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2C4 unconjugated
anti-Integrin beta 5 (ITGB5) (AA 137-378) antibodyITGB5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 5 (ITGB5) (AA 136-378) antibodyITGB5 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 5 (ITGB5) (C-Term) antibodyITGB5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 5 (ITGB5) (AA 490-720) antibodyITGB5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 5 (ITGB5) (C-Term) antibodyITGB5 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 5 (ITGB5) (AA 421-516) antibodyITGB5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Integrin beta 5 (ITGB5) (C-Term) antibodyITGB5 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 5 (ITGB5) (AA 1-799) antibodyITGB5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 5 (ITGB5) (AA 216-244), (N-Term) antibodyITGB5 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33832 unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- Integrin beta 5 (ITGB5)
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别名
- Integrin beta-5 / ITGB5
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背景
- Integrins are heterodimers composed of noncovalently associated transmembrane alpha and beta subunits. The 16alpha and 8beta subunits heterodimerize to produce more than 20 different receptors. Most Integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain Integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster Integrins by binding to adjacent Integrin receptors, both receptor clustering and ligand occupancy are necessary for the activation of Integrinmediated responses. In addition to mediating cell adhesion and cytoskeletal organization, Integrins function as signaling receptors. Signals transduced by Integrins play a role in many ,biological processes, including cell growth, differentiation, migration and apoptosis.Synonyms: ITGB-5
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分子量
- approx. 88 kDa
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基因ID
- 3693
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NCBI登录号
- NP_002204
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UniProt
- P18084
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途径
- Integrin Complex
抗原
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