HSPA9 抗体
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北京 101111
Quick Overview for HSPA9 抗体 (ABIN265446)
抗原
See all HSPA9 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of GRP75/HSPA9 protein.
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) (C-Term) antibody
HSPA9 适用: 人, 大鼠, 小鼠, 犬, 兔, Cow, 豚鼠, 马 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) (AA 1-679) antibodyHSPA9 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) antibodyHSPA9 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) (C-Term) antibodyHSPA9 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) (C-Term) antibodyHSPA9 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, FACS 宿主: 小鼠 Monoclonal 4I9 unconjugated
anti-Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) (AA 561-679) antibodyHSPA9 适用: 人, 大鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) (AA 646-679), (C-Term) antibodyHSPA9 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, IP, FACS 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) (C-Term) antibodyHSPA9 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) (AA 1-679) antibodyHSPA9 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) (C-Term) antibodyHSPA9 适用: 人, 大鼠, 小鼠, 猴, 兔, Drosophila melanogaster, Hamster, 马, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/5000approx. 1/40000. Western Bot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- HSPA9 (Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9))
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别名
- Grp75 / HSPA9
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背景
- The HSP 70 family comprises four highly conserved proteins, HSP 70, HSC 70, GRP 75 and GRP 78, which serve a variety of roles. They act as molecular chaperones facilitating the assembly of multi-protein complexes, participate in the translocation of polypeptides across cell membranes and to the nucleus, and aid in the proper folding of nascent polypeptide chains. HSC 70, GRP 75 and GRP 78 are constitutively expressed in primate cells. HSP 70 expression is strongly induced in response to heat stress. HSP 70 and HSC 70, which are found in both the cytosol and nucleus of mammalian cells, play key roles in the cytosolic endoplasmic reticulum and mitochondrial import machinery. They are involved in chaperoning nascent polypeptide chains and in protecting cells against the accumulation of improperly folded proteins. GRP 75 and GRP 78 are unresponsive to heat stress and are induced by glucose deprivation. GRP 75 expression is restricted to the mitochondrial matrix and aids in the translocation and folding of nascent polypeptide chains of both nuclear and mitochondrial origin. GRP 78 is localized in the endoplasmic reticulum, where it receives imported secretory proteins and is involved in the folding and translocation of nascent peptide chains. Research indicates that members of the HSP 70 family may act as force-generating motors, relying on the hydrolysis of ATP for their activity.Synonyms: 75 kDa glucose-regulated protein, HSPA9B, Heat shock 70 kDa protein 9, MOT, Mortalin, PBP74, Peptide-binding protein 74, Stress-70 protein
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分子量
- approx. 90 kDa
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基因ID
- 3313
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NCBI登录号
- NP_004125
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UniProt
- P38646
抗原
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