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GRM7 抗体

This anti-GRM7 antibody is a 兔 多克隆 antibody detecting GRM7 in WB, IF, IHC (p) 和 EIA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN265440
发货至: 中国

Quick Overview for GRM7 抗体 (ABIN265440)

抗原

See all GRM7 抗体
GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

适用

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人, 大鼠, 小鼠

宿主

  • 34
  • 11
  • 1

克隆类型

  • 35
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多克隆

标记

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This GRM7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of mGluR7 protein. (region surrounding Glu894)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen
  • 应用备注

    ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

    别名

    mGluR7 / GRM7

    背景

    The mGluR proteins (metabotropic glutamate receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-7, which can interact with PRKCABP, acts as a receptor for glutamate. It is highly expressed in various areas of the brain, but highest levels are detected in cerebellum, cerebral cortex and hippocampus.Synonyms: GPRC1G, MGLUR7, Metabotropic glutamate receptor 7

    分子量

    approx. 100 kDa

    基因ID

    2917

    NCBI登录号

    NP_000835

    UniProt

    Q14831

    途径

    Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour
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