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Gastrin 抗体

GAST 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265432
发货至: 中国
  • 抗原 See all Gastrin (GAST) 抗体
    Gastrin (GAST)
    适用
    • 53
    • 32
    • 28
    • 6
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 55
    • 11
    • 1
    克隆类型
    • 56
    • 11
    多克隆
    标记
    • 38
    • 9
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Gastrin antibody is un-conjugated
    应用范围
    • 54
    • 30
    • 25
    • 14
    • 13
    • 13
    • 12
    • 11
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Gastrin protein. (region surrounding Met90)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product GAST Primary Antibody
  • 应用备注
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    Gastrin (GAST)
    别名
    Gastrin (GAST 产品)
    别名
    GAS antibody, Gas antibody, PPG34 antibody, GAST antibody, gastrin antibody, GAST antibody, Gast antibody
    背景
    Gastrin, which is normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets, is a hormone whose main function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. Gastrin also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. Gastrin is regulated by epidermal growth factor in both mice and humans. Gastrin is excreted in excess by pancreatic tumors in the Zollinger- Ellison syndrome. Gastrin maps to human chromosome 17q-21. Gastrin- Releasing Peptide (GRP) stimulates the release of gastrin as well as other gastrointestinal hormones, in addition to acting as an autocrine growth factor for certain cell types. High levels of GRP are found in the human lung just after birth and levels decrease thereafter in parallel with the observed disease in a number of pulmonary neuroendocrine cells. GRP is known to promote lung tumorigenesis in model systems and, interestingly, is induced by retinoic acid. GRP is involved in several functions with the hypothalamus,and is thought to play a role in regulating pituitary hormone secretion. GRP maps to human chromosome 18q21.Synonyms: GAS, GAST
    分子量
    approx. 12 kDa
    基因ID
    2520
    NCBI登录号
    NP_000796
    UniProt
    P01350
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