Gastrin 抗体
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北京 101111
Quick Overview for Gastrin 抗体 (ABIN265432)
抗原
See all Gastrin (GAST) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Gastrin protein. (region surrounding Met90)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Gastrin (GAST) (AA 1-101) antibody
GAST 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) (C-Term) antibodyGAST 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) (AA 77-92) antibodyGAST 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) (AA 1-101) antibodyGAST 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7G5 unconjugated
anti-Gastrin (GAST) (AA 52-101) antibodyGAST 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) (Center) antibodyGAST 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) (AA 1-104) antibodyGAST 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) antibodyGAST 适用: 人 ELISA 宿主: 小鼠 Monoclonal GAST-2631 unconjugated
anti-Gastrin (GAST) antibodyGAST 适用: 人 ELISA 宿主: 小鼠 Monoclonal GAST-2632 unconjugated
anti-Gastrin (GAST) (AA 49-78) antibodyGAST 适用: 人 WB 宿主: 小鼠 Monoclonal 486CT4-8-13-6 unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- Gastrin (GAST)
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别名
- Gastrin
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背景
- Gastrin, which is normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets, is a hormone whose main function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. Gastrin also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. Gastrin is regulated by epidermal growth factor in both mice and humans. Gastrin is excreted in excess by pancreatic tumors in the Zollinger- Ellison syndrome. Gastrin maps to human chromosome 17q-21. Gastrin- Releasing Peptide (GRP) stimulates the release of gastrin as well as other gastrointestinal hormones, in addition to acting as an autocrine growth factor for certain cell types. High levels of GRP are found in the human lung just after birth and levels decrease thereafter in parallel with the observed disease in a number of pulmonary neuroendocrine cells. GRP is known to promote lung tumorigenesis in model systems and, interestingly, is induced by retinoic acid. GRP is involved in several functions with the hypothalamus,and is thought to play a role in regulating pituitary hormone secretion. GRP maps to human chromosome 18q21.Synonyms: GAS, GAST
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分子量
- approx. 12 kDa
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基因ID
- 2520
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NCBI登录号
- NP_000796
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UniProt
- P01350
抗原
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