Filamin A 抗体
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北京 101111
Quick Overview for Filamin A 抗体 (ABIN265421)
抗原
See all Filamin A (FLNA) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Filamin A protein. (region surrounding Arg5146)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Filamin A, alpha (FLNA) (AA 2-274) antibody
FLNA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Filamin A, alpha (FLNA) (AA 1-838) antibodyFLNA 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 4E10-1B2 unconjugated
anti-Filamin A, alpha (FLNA) (pSer2152) antibodyFLNA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Filamin A, alpha (FLNA) antibodyFLNA 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Filamin A, alpha (FLNA) (AA 451-638) antibodyFLNA 适用: 人 WB, IHC, IF 宿主: 小鼠 Monoclonal 3F8 unconjugated
anti-Filamin A, alpha (FLNA) (AA 1819-2068) antibodyFLNA 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Filamin A, alpha (FLNA) (AA 1725-1775) antibodyFLNA 适用: 人 IHC, IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Filamin A, alpha (FLNA) (AA 1025-1054) antibodyFLNA 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB14246 unconjugated
anti-Filamin A, alpha (FLNA) (AA 1-838) antibodyFLNA 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B6-1D10 unconjugated
anti-Filamin A, alpha (FLNA) (AA 1234-1462) antibodyFLNA 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 1000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Filamin A (FLNA) (Filamin A, alpha (FLNA))
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别名
- Filamin-A
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背景
- Caldesmon, Filamin 1, nebulin and villin are differentially expressed and regulated Actin binding proteins. Both muscular (CDh) and non-muscular (CDl) forms of caldesmon have been identified and each has been shown to bind to Actin as well as to calmodulin and Myosin. CDh is expressed predominantly on thin filaments in smooth muscle, whereas CDl is widely expressed in nonmuscle tissues and cells. Filamin 1, which is ubiquitously expressed and exists as a homodimer, functions to crosslink Actin to filaments. Nebulin is a large filamentous protein specific to muscle tissue that may function as a ruler for filament length. Several isoforms of nebulin, ranging from 700 to 900 kDa, are produced by alternative exon usage. Villin is Ca2+-regulated and is the major structural component of the brush border of absorptive cells.Synonyms: Actin-binding protein 280, Alpha-filamin, Endothelial actin-binding protein, FLN, FLN1, FLNA, Filamin-1, Non-muscle filamin
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分子量
- approx. 280 kDa
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基因ID
- 2316
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NCBI登录号
- NP_001104026
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UniProt
- P21333
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途径
- TCR Signaling, Maintenance of Protein Location
抗原
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