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FGFR1OP 抗体

The 兔 多克隆 anti-FGFR1OP antibody (ABIN265416) specifically detects FGFR1OP in WB, IF 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN265416
发货至: 中国
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Quick Overview for FGFR1OP 抗体 (ABIN265416)

抗原

See all FGFR1OP 抗体
FGFR1OP (FGFR1 Oncogene Partner (FGFR1OP))

适用

  • 67
  • 21
  • 18
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 60
  • 7
  • 2

克隆类型

  • 60
  • 9
多克隆

标记

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  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FGFR1OP antibody is un-conjugated

应用范围

  • 60
  • 26
  • 26
  • 15
  • 14
  • 11
  • 8
  • 6
  • 6
  • 3
  • 3
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of FGFR1OP protein (region surrounding Asn371).

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen

    纯度

    > 95 % pure by SDS-PAGE
  • 应用备注

    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    FGFR1OP (FGFR1 Oncogene Partner (FGFR1OP))

    别名

    FGFR1OP

    背景

    Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors. These include the Flg receptor or FGFR-1, the Bek receptor or FGFR-2, FGFR-3, FGFR-4, FGFR-5 and FGFR-6. These receptors usually contain an extracellular ligand-binding region containing three immunoglobulin-like domains, a transmembrane domain and a cytoplasmic tyrosine kinase domain. The gene encoding human Flg maps to chromosome 8p11 and is alternatively spliced to produce several isoforms. Mutations in Flg are associated with Pfeiffer syndrome, a skeletal disorder characterized by craniosynostosis with deviation and enlargement of the thumbs and great toes, brachymesophalangy, with phalangeal ankylosis and a varying degree of soft tissue syndactyly. The Flg gene is also involved in chromosomal translocations with ZNF198, CEP110 and FOP, which may lead to stem cell leukemia lymphoma (SCLL).Synonyms: FGFR1 oncogene partner, FOP

    分子量

    approx. 43, 92 kDa

    基因ID

    11116

    NCBI登录号

    NP_008976

    UniProt

    O95684

    途径

    M Phase, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
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