Claudin 3 抗体
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- 抗原 See all Claudin 3 (CLDN3) 抗体
- Claudin 3 (CLDN3)
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Claudin 3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of Claudin-3 protein. (region surrounding Thr204)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity-Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product CLDN3 Primary Antibody
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anti-Claudin 3 (CLDN3) (C-Term) antibody
CLDN3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) (Ser255) antibodyCLDN3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) antibodyCLDN3 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) (AA 181-220) antibodyCLDN3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) (C-Term) antibodyCLDN3 适用: 人, Cow WB, IHC, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) (AA 171-220) antibodyCLDN3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) (C-Term) antibodyCLDN3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) (AA 30-159) antibodyCLDN3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) antibodyCLDN3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) (C-Term) antibodyCLDN3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/40000-1/60000. Western blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Claudin 3 (CLDN3)
- 别名
- Claudin-3 / CLDN3 (CLDN3 产品)
- 别名
- claudin-3 antibody, cpe-r2 antibody, cpetr2 antibody, hrvp1 antibody, rvp1 antibody, CLDN3 antibody, LOC100228090 antibody, C7orf1 antibody, CPE-R2 antibody, CPETR2 antibody, HRVP1 antibody, RVP1 antibody, AI182374 antibody, Cpetr2 antibody, mRVP1 antibody, claudin 3 L homeolog antibody, claudin 3 antibody, claudin-4-like antibody, cldn3.L antibody, cldn3 antibody, CLDN3 antibody, LOC100228090 antibody, Cldn3 antibody
- 背景
- The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is highly restricted to specfic regions of different tissues and variations of Claudin expression may have an important role in transcellular transport through tight junctions. In rat liver, claudin-3 is uniformly expressed, whereas in the pancreas, claudin-3 is expressed in junctions of the duct epithelia and junctions of acinar cells. Claudin-3 binds the peptide toxin Clostridium perfringens enterotoxin (CPE) at the cell surface via the second extracellular loop of claudin-3. The gene encoding human claudin-3 maps to chromosome 7q11.23.Synonyms: C7orf1, CPE-R2, CPE-Receptor 2, CPETR2, Clostridium perfringens enterotoxin receptor 2, RVP1
- 分子量
- approx. 25 kDa
- 基因ID
- 1365
- NCBI登录号
- NP_001297
- UniProt
- O15551
- 途径
- Hepatitis C
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